Analytical and Clinical Validation of Expressed Variants and Fusions From the Whole Transcriptome of Thyroid FNA Samples

Introduction: The Afirma® Xpression Atlas (XA) detects gene variants and fusions in thyroid nodule FNA samples from a curated panel of 511 genes using whole-transcriptome RNA-sequencing. Its intended use is among cytologically indeterminate nodules that are Afirma GSC suspicious, Bethesda V/VI nodul...

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Main Authors: Trevor E. Angell, Lori J. Wirth, Maria E. Cabanillas, Maisie L. Shindo, Edmund S. Cibas, Joshua E. Babiarz, Yangyang Hao, Su Yeon Kim, P. Sean Walsh, Jing Huang, Richard T. Kloos, Giulia C. Kennedy, Steven G. Waguespack
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-09-01
Colecção:Frontiers in Endocrinology
Assuntos:
molecular diagnostics
thyroid cancer
fine-needle aspiration
thyroid molecular assays
RNA-sequencing
transcriptome
Acesso em linha:https://www.frontiersin.org/article/10.3389/fendo.2019.00612/full
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