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DJ-1-dependent regulation of oxidative stress in the retinal pigment epithelium (RPE).

DJ-1 is found in many tissues, including the brain, where it has been extensively studied due to its association with Parkinson's disease. DJ-1 functions as a redox-sensitive molecular chaperone and transcription regulator that robustly protects cells from oxidative stress.Retinal pigment epith...

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Autores principales: Karen G Shadrach, Mary E Rayborn, Joe G Hollyfield, Vera L Bonilha
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2013-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC3699467?pdf=render
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