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DJ-1-dependent regulation of oxidative stress in the retinal pigment epithelium (RPE).
DJ-1 is found in many tissues, including the brain, where it has been extensively studied due to its association with Parkinson's disease. DJ-1 functions as a redox-sensitive molecular chaperone and transcription regulator that robustly protects cells from oxidative stress.Retinal pigment epith...
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Autores principales: | , , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Public Library of Science (PLoS)
2013-01-01
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Colección: | PLoS ONE |
Acceso en línea: | http://europepmc.org/articles/PMC3699467?pdf=render |
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