Potential genetic modifiers for somatic EGFR mutation in lung cancer: a meta-analysis and literature review

Abstract Background Accumulating evidence indicates inherited risk in the aetiology of lung cancer, although smoking exposure is the major attributing factor. Family history is a simple substitute for inherited susceptibility. Previous studies have shown some possible yet conflicting links between f...

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Bibliographic Details
Main Authors: Yue I. Cheng, Yun Cui Gan, Dan Liu, Michael P. A. Davies, Wei Min Li, John K. Field
Format: Artigo
Language:Inglês
Published: BMC 2019-11-01
Series:BMC Cancer
Subjects:
Lung cancer
EGFR mutation
Family history of cancer
Inherited susceptibility
Cancer predisposition genes
EGFR T790 M
Online Access:http://link.springer.com/article/10.1186/s12885-019-6317-6
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