Tubeimoside 1 Acts as a Chemotherapeutic Synergist via Stimulating Macropinocytosis

Macropinocytosis is a highly conserved endocytic process which characterizes the engulfment of extracellular fluid and its contents into cells via large, heterogeneous vacuoles known as macropinosomes. Tubeimoside-1 (TBM1) is a low toxic triterpenoid saponin extracted from a traditional Chinese herb...

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Detalhes bibliográficos
Main Authors: Xianling Gong, Ruibo Sun, Zhuowei Gao, Weili Han, Yawei Liu, Liang Zhao, Linlin Jing, Xueqing Yao, Xuegang Sun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-09-01
Colecção:Frontiers in Pharmacology
Assuntos:
tubeimoside 1
chemotherapeutic synergist
macropinocytosis
methuosis
endocytosis
Acesso em linha:https://www.frontiersin.org/article/10.3389/fphar.2018.01044/full
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