Infiltration of inflammatory macrophages and neutrophils and widespread pyroptosis in lung drive influenza lethality in nonhuman primates.

Severe influenza kills tens of thousands of individuals each year, yet the mechanisms driving lethality in humans are poorly understood. Here we used a unique translational model of lethal H5N1 influenza in cynomolgus macaques that utilizes inhalation of small-particle virus aerosols to define mecha...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Jacqueline Corry, Gwenddolen Kettenburg, Amit A Upadhyay, Megan Wallace, Michelle M Marti, Elizabeth R Wonderlich, Stephanie J Bissel, Kyndal Goss, Timothy J Sturgeon, Simon C Watkins, Douglas S Reed, Steven E Bosinger, Simon M Barratt-Boyes
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2022-03-01
Seri Bilgileri:PLoS Pathogens
Online Erişim:https://doi.org/10.1371/journal.ppat.1010395
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller