Determination of lipophilicity of some new 1,2,4-triazole derivatives by RP-HPLC and RP-TLC and calculated methods

Experimental and computational approaches were used to estimate the lipophilicity of novel 1,2,4-triazole derivatives. These derivatives have been subjected to this research, because they exhibit antimicrobial activity. The chromatographic analysis of RP-HPLC and RP-TLC was carried out using methano...

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Hlavní autoři: Anna M. Hawrył, Ryszard S. Świeboda, Mateusz S. Gawroński, Magdalena A. Wójciak-Kosior, Łukasz P. Popiołek, Ryszard B. Kocjan
Médium: Artigo
Jazyk:Inglês
Vydáno: Growing Science 2015-06-01
Edice:Current Chemistry Letters
Témata:
lipophilicity
1
2
4-triazole derivatives Computed logP
RP-HPLC
RP-TLC
PCA
On-line přístup:http://www.growingscience.com/ccl/Vol4/ccl_2015_9.pdf
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