Pro-apoptotic Effect of Pifithrin-α on Preimplantation Porcine Fertilized Embryo Development

The aim of this study was to investigate the impact of a reported p53 inhibitor, pifithrin-α (PFT-α), on preimplantation porcine in vitro fertilized (IVF) embryo development in culture. Treatment of PFT-α was administered at both early (0 to 48 hpi), and later stages (48 to 168 hpi) of preimplantati...

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Detalles Bibliográficos
Main Authors: Brendan Mulligan, Jae-Yeon Hwang, Hyung-Min Kim, Jong-Nam Oh, Kwang-Hwan Choi, Chang-Kyu Lee
Formato: Artigo
Idioma:Inglês
Publicado: Asian-Australasian Association of Animal Production Societies 2012-12-01
Series:Asian-Australasian Journal of Animal Sciences
Assuntos:
Apoptosis
Fertilization
Pifithrin-α
Blastocyst
Preimplantation Embryo
Pig
Acceso en liña:http://www.ajas.info/upload/pdf/25-219.pdf
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