Synthesis and in vitro evaluation of a novel thienopyrimidine with phototoxicity towards rat glioma F98 cells

Glioblastoma multiforme is one of the most aggressive cancer forms in humans, and has low recovery rates after surgery, ionizing radiation and chemotherapy. Therefore, there is a high interest in the development of new treatment methods, as for instance photodynamic therapy (PDT). It is here present...

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Main Authors: Odrun A Gederaas, Andreas S Sørensen, Mikael Lindgren, Thor Bernt Melø, Dag Altin, Ellen MS Flatby, Anders Høgset, Bård Helge Hoff
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-06-01
Colecção:Journal of Photochemistry and Photobiology
Assuntos:
Pyrimidine
Cytotoxicity
PDT
Photophysics
In vitro studies
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2666469022000070
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