Ischemic Postconditioning-Regulated miR-499 Protects the Rat Heart Against Ischemia/Reperfusion Injury by Inhibiting Apoptosis through PDCD4

Background: Here, we determined miR-499 involvement in the protective effect of ischemic postconditioning (IPC) against myocardial ischemia/reperfusion (I/R) injury and identified the underlying mechanisms. Methods: To investigate the cardioprotective effect of IPC-induced miR-499, rats were divided...

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Detalhes bibliográficos
Main Authors: Jianbing Zhu, Kang Yao, Qian Wang, Junjie Guo, Hongtao Shi, Leilei Ma, Haibo Liu, Wei Gao, Yunzeng Zou, Junbo Ge
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Physiol Biochem Press GmbH & Co KG 2016-11-01
Colecção:Cellular Physiology and Biochemistry
Assuntos:
Ischemic postconditioning
miR-499
Ischemia/reperfusion
Apoptosis
PDCD4
Acesso em linha:http://www.karger.com/Article/FullText/452506
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