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Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway [version 2; referees: 2 approved, 2 approved with reservations]
Background. Tuberculosis remains a major global health concern. The ability to prevent phagosome-lysosome fusion is a key mechanism by which intracellular mycobacteria, including Mycobacterium tuberculosis, achieve long-term persistence within host cells. The mechanisms underpinning this key intrace...
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Main Authors: | , , , , , , , , , , , , , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Wellcome
2017-06-01
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Serier: | Wellcome Open Research |
Fag: | |
Online adgang: | https://wellcomeopenresearch.org/articles/1-18/v2 |
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