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Update on the Use of L-Asparaginase in Infants and Adolescent Patients with Acute Lymphoblastic Leukemia

Great improvements have been made in acute lymphoblastic leukemia (ALL) treatment in the past decades, especially due to the use of L-asparaginase (L-ASP). Despite the significant success rate, several side effects mainly caused by toxicity, asparaginase silent inactivation, and cellular resistance,...

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Главные авторы: Augusto F. Andrade, Kleiton S. Borges, Vanessa S. Silveira
Формат: Artigo
Язык:Inglês
Опубликовано: SAGE Publishing 2014-01-01
Серии:Clinical Medicine Insights: Oncology
Online-ссылка:https://doi.org/10.4137/CMO.S10242
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