Tunicamycin promotes metastasis through upregulating endoplasmic reticulum stress induced GRP78 expression in thyroid carcinoma

Abstract Background Thyroid cancer (TC) is the most common type of endocrine malignancy and its incidence is increasing over years. Conventional surgery, radiotherapy and chemotherapy are difficult to improve the significant effects of it due to aggression and metastasis of poorly differentiated thy...

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Hlavní autoři: Guohong Zhao, Jianqin Kang, Guanghui Xu, Jing Wei, Xiaoguang Wang, Xiaorui Jing, Lan Zhang, Aili Yang, Kai Wang, Jue Wang, Li Wang, Junfeng Hou, Qingquan Liu, Kai Jiao, Bin Gao
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2020-10-01
Edice:Cell & Bioscience
Témata:
Tunicamycin
Metastasis
ER stress
GRP78
Thyroid cancer
On-line přístup:http://link.springer.com/article/10.1186/s13578-020-00478-0
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