Characterization of cell-cell communication in autistic brains with single-cell transcriptomes

Abstract Background Autism spectrum disorder is a neurodevelopmental disorder, affecting 1–2% of children. Studies have revealed genetic and cellular abnormalities in the brains of affected individuals, leading to both regional and distal cell communication deficits. Methods Recent application of si...

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Bibliographic Details
Main Authors: Maider Astorkia, Herbert M. Lachman, Deyou Zheng
Format: Artigo
Language:Inglês
Published: BMC 2022-05-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
Cell-cell communication
Ligand-receptor
Single-cell RNA-seq
Brain
Autism
Network
Online Access:https://doi.org/10.1186/s11689-022-09441-1
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