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Inhibition of expression in Escherichia coli of a virulence regulator MglB of Francisella tularensis using external guide sequence technology.

External guide sequences (EGSs) have successfully been used to inhibit expression of target genes at the post-transcriptional level in both prokaryotes and eukaryotes. We previously reported that EGS accessible and cleavable sites in the target RNAs can rapidly be identified by screening random EGS...

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Bibliografiske detaljer
Main Authors: Gaoping Xiao, Eirik W Lundblad, Mina Izadjoo, Sidney Altman
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2008-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC2579583?pdf=render
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