Impact of high drinking water nitrate levels on the endogenous formation of apparent N-nitroso compounds in combination with meat intake in healthy volunteers

Abstract Background Nitrate is converted to nitrite in the human body and subsequently can react with amines and amides in the gastrointestinal tract to form N-nitroso compounds (NOCs), which are known to be carcinogenic in animals. Humans can be exposed to nitrate via consumption of drinking water...

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Main Authors: Simone G. van Breda, Karen Mathijs, Virág Sági-Kiss, Gunter G. Kuhnle, Ben van der Veer, Rena R. Jones, Rashmi Sinha, Mary H. Ward, Theo M. de Kok
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMC 2019-10-01
Sraith:Environmental Health
Ábhair:
Nitrate
Nitrite
Drinking water
Processed red and unprocessed white meat
Human dietary intervention study
N-nitroso compounds
Rochtain Ar Líne:http://link.springer.com/article/10.1186/s12940-019-0525-z
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