Deciphering Risperidone-Induced Lipogenesis by Network Pharmacology and Molecular Validation

BackgroundRisperidone is an atypical antipsychotic that can cause substantial weight gain. The pharmacological targets and molecular mechanisms related to risperidone-induced lipogenesis (RIL) remain to be elucidated. Therefore, network pharmacology and further experimental validation were undertake...

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Bibliographische Detailangaben
Hauptverfasser: Yun Fu, Ke Yang, Yepei Huang, Yuan Zhang, Shen Li, Wei-Dong Li
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2022-04-01
Schriftenreihe:Frontiers in Psychiatry
Schlagworte:
risperidone
lipogenesis
network pharmacology
molecular docking
lipolysis
beta oxidation
Online Zugang:https://www.frontiersin.org/articles/10.3389/fpsyt.2022.870742/full
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