Molecular Characteristics of T Cell-Mediated Tumor Killing in Hepatocellular Carcinoma

BackgroundAlthough checkpoint blockade is a promising approach for the treatment of hepatocellular carcinoma (HCC), subsets of patients expected to show a response have not been established. As T cell-mediated tumor killing (TTK) is the fundamental principle of immune checkpoint inhibitor therapy, w...

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Detalhes bibliográficos
Main Authors: Wei-feng Hong, Mou-yuan Liu, Li Liang, Yang Zhang, Zong-juan Li, Keqi Han, Shi-suo Du, Yan-jie Chen, Li-heng Ma
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-04-01
Colecção:Frontiers in Immunology
Assuntos:
hepatocellular carcinoma
T cell-mediated tumor killing
tumor microenvironment
glycolipid metabolism
somatic mutation analysis
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fimmu.2022.868480/full
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