Novel CFTR Activator Cact-3 Ameliorates Ocular Surface Dysfunctions in Scopolamine-Induced Dry Eye Mice

Cystic fibrosis transmembrane conductance regulator (CFTR) is highly expressed on the ocular epithelium and plays a pivotal role in the fluid secretion driven by chloride transport. Dry eye disease is one of the most common diseases with limited therapeutic options. In this study, a high-throughput...

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Detalhes bibliográficos
Main Authors: Dongkyu Jeon, Ikhyun Jun, Ho K. Lee, Jinhong Park, Bo-Rahm Kim, Kunhi Ryu, Hongchul Yoon, Tae-im Kim, Wan Namkung
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2022-05-01
Colecção:International Journal of Molecular Sciences
Assuntos:
CFTR
activator
Cact-3
dry eye disease
scopolamine
Acesso em linha:https://www.mdpi.com/1422-0067/23/9/5206
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