Effects of Cyclooxygenase Inhibitors in Combination with Taxol on Expression of Cyclin D1 and Ki-67 in a Xenograft Model of Ovarian Carcinoma

The present study was designed to investigate the effects of cyclooxygenase (COX) inhibitors in combination with taxol on the expression of cyclin D1 and Ki-67 in human ovarian SKOV-3 carcinoma cells xenograft-bearing mice. The animals were treated with 100 mg/kg celecoxib (a COX-2 selective inhibit...

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Main Authors: Liang Wan, Jun Zhang, Jia-Hui Cai, Wei Li, Yun-Xian Tang
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2012-08-01
Series:International Journal of Molecular Sciences
Assuntos:
ovarian carcinoma
SC-560
celecoxib
taxol
cyclin D1
cell proliferation
Acceso en liña:http://www.mdpi.com/1422-0067/13/8/9741
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