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An Antisense Oligonucleotide against a Splicing Enhancer Sequence within Exon 1 of the <i>MSTN</i> Gene Inhibits Pre-mRNA Maturation to Act as a Novel Myostatin Inhibitor
Antisense oligonucleotides (ASOs) are agents that modulate gene function. ASO-mediated out-of-frame exon skipping has been employed to suppress gene function. Myostatin, encoded by the <i>MSTN</i> gene, is a potent negative regulator of skeletal muscle growth. ASOs that induce skipping o...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2022-04-01
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| Colecção: | International Journal of Molecular Sciences |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/1422-0067/23/9/5016 |
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