Compatibility of Fuzi and Ginseng Significantly Increase the Exposure of Aconitines

The herb-pair ginseng-Fuzi (the root of Aconitum carmichaelii) is the material basis of Shenfu prescriptions and is popular in traditional Chinese medicine for the treatment of heart failure, and even shock with severe-stage of COVID-19. A narrow therapeutic window of Fuzi may cause significant regi...

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Detalhes bibliográficos
Main Authors: Ze-Yan Chen, Xu-Ya Wei, Zi-Dong Qiu, Yun Huang, Ting Tan, Yu-Lin Feng, Juan Guo, Guang-Hong Cui, Lu-Qi Huang, Chang-Jiang-Sheng Lai
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2022-04-01
Colecção:Frontiers in Pharmacology
Assuntos:
Aconitum carmichaelii
ginseng
pharmacokinetics
aconitine
high performance liquid chromatography-mass spectrometry
COVID-19
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2022.883898/full
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