Rs145204276 and rs4759314 affect the prognosis of prostate cancer by modulating the GAS5/miR-1284/HMGB1 and HOTAIR/miR-22/HMGB1 signalling pathways

Non-coding RNAs play an important role in the pathogenesis of prostate cancer (PC). This study aims to characterize the role of GAS5 rs145204276 and HOTAIR rs4759314 polymorphisms in the pathogenesis of PC. Both INS allele of GAS5 rs145204276 and A allele of HOTAIR rs4759314 were identified to incre...

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Detalhes bibliográficos
Main Authors: Zhi-Hai Deng, Gan-Shen Yu, Bin Pan, Zhen-Hua Feng, Qiang Huang, Jian-Zhong Deng, Bo Chen, Shi-Kun Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2020-01-01
Colecção:Artificial Cells, Nanomedicine, and Biotechnology
Assuntos:
Prostate cancer
rs145204276
rs4759314
miR-1284
miR-22
GAS5
Acesso em linha:https://www.tandfonline.com/doi/10.1080/21691401.2019.1709859
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