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Gonadal Failure Is Common in Long-Term Survivors of Childhood High-Risk Neuroblastoma Treated With High-Dose Chemotherapy and Autologous Stem Cell Rescue

Background: Neuroblastoma is the most common extra-cranial solid tumor in children. Intensive therapy including autologous stem-cell transplantation (HSCT) has improved the poor prognosis of high-risk neuroblastoma (HR-NBL) but may impair gonadal function.Objectives: To investigate the gonadal funct...

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Detalhes bibliográficos
Main Authors: Pauliina Utriainen, Anu Suominen, Outi Mäkitie, Kirsi Jahnukainen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-08-01
Colecção:Frontiers in Endocrinology
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Acesso em linha:https://www.frontiersin.org/article/10.3389/fendo.2019.00555/full
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