The study of establishment of an in vivo tumor model by three-dimensional cells culture systems methods and evaluation of antitumor effect of biotin-conjugated pullulan acetate nanoparticles

In this study, three-dimensional (3D) hydrogels were used for human hepatocellular carcinoma (HepG2) cells culture systems in vitro and establishment of an in vivo xenografted tumor model. Based on our previous work on the biotin-conjugated pullulan acetate nanoparticles (Bio-PA NPs) as anticancer d...

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Main Authors: Hongli Chen, Xiangjuan Wei, Hongyang Chen, Hongliang Wei, Yongxue Wang, Wenbin Nan, Qiqing Zhang, Xuejun Wen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2019-12-01
Colecção:Artificial Cells, Nanomedicine, and Biotechnology
Assuntos:
Two-dimensional cells culture
three-dimensional cells culture
nanoparticles
pullulan
targeted antitumor
Acesso em linha:https://www.tandfonline.com/doi/10.1080/21691401.2018.1544142
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