Lymphocyte homeostasis is maintained in perinatally HIV-infected patients after three decades of life

Abstract Background While immunosenescence, defined as reduced production of new lymphocytes, restriction of T-cell receptor repertoire and telomeres shortening, has been extensively evaluated in HIV-infected children and adults, no data about these parameters are available in perinatally-infected p...

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Bibliographic Details
Main Authors: S. Paghera, E. Quiros-Roldan, A. Sottini, M. Properzi, F. Castelli, L. Imberti
Format: Artigo
Language:Inglês
Published: BMC 2019-10-01
Series:Immunity & Ageing
Subjects:
Perinatal HIV infection
Immunosenescence
T-cell receptor repertoire
Telomere length
Thymic and bone marrow output
Online Access:http://link.springer.com/article/10.1186/s12979-019-0166-7
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