Porcine parvovirus triggers autophagy through the AMPK/Raptor/mTOR pathway to promote viral replication in porcine placental trophoblasts

Abstract Autophagy has been demonstrated to play important roles in the infection and pathogenesis of many viruses. We previously found that porcine parvovirus (PPV) infection can induce autophagy in porcine placental trophoblast cells (PTCs), but its underlying mechanism has not yet been fully reve...

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Detalhes bibliográficos
Main Authors: Xiujuan Zhang, Peipei Ma, Ting Shao, Yingli Xiong, Qian Du, Songbiao Chen, Bichen Miao, Xuezhi Zhang, Xiaoya Wang, Yong Huang, Dewen Tong
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-05-01
Colecção:Veterinary Research
Assuntos:
Porcine parvovirus
placental trophoblast cells
autophagy
signalling pathway
Acesso em linha:https://doi.org/10.1186/s13567-022-01048-7
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