Evidence for the Effect of Vaccination on Host-Pathogen Interactions in a Murine Model of Pulmonary Tuberculosis by Mycobacterium tuberculosis

The global control of Tuberculosis remains elusive, and Bacillus Calmette-Guérin (BCG) -the most widely used vaccine in history—has proven insufficient for reversing this epidemic. Several authors have suggested that the mass presence of vaccinated hosts might have affected the Mycobacterium tubercu...

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Main Authors: Zyanya Lucia Zatarain-Barrón, Octavio Ramos-Espinosa, Brenda Marquina-Castillo, Jorge Barrios-Payán, Fernanda Cornejo-Granados, Otoniel Maya-Lucas, Gamaliel López-Leal, Camilo Molina-Romero, Richard M. Anthony, Adrián Ochoa-Leyva, Inti Alberto De La Rosa-Velázquez, Rosa Gloria Rebollar-Vega, Robin M. Warren, Dulce Adriana Mata-Espinosa, Rogelio Hernández-Pando, Dick van Soolingen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-05-01
Colecção:Frontiers in Immunology
Assuntos:
tuberculosis
BCG vaccination
Beijing genotype
virulence
lung transcriptome
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2020.00930/full
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