Variation in blood microbial lipopolysaccharide (LPS) contributes to immune reconstitution in response to suppressive antiretroviral therapy in HIV

Summary: Background: In HIV infection, even under long-term antiretroviral therapy (ART), up to 20% of HIV-infected individuals fail to restore CD4+ T cell counts to the levels similar to those of healthy controls. The mechanisms of poor CD4+ T cell reconstitution on suppressive ART are not fully u...

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Detalhes bibliográficos
Main Authors: Zhenwu Luo, Sonya L. Health, Min Li, Hyojik Yang, Yongxia Wu, Michael Collins, Steven G. Deeks, Jeffrey N. Martin, Alison Scott, Wei Jiang
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-06-01
Colecção:EBioMedicine
Assuntos:
HIV
Immune non-responders
Immune responders
Lipopolysaccharide
Lipid A
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352396422002183
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