Efficacy of Local Minocycline Agents in Treating Peri-Implantitis: An Experimental In Vivo Study in Beagle Dogs

Background: Local delivery agents (LDA) have the advantage of delivering the antibiotics at high concentrations to the targeted sites. However, the constant flow of gingival crevicular fluids and saliva may restrict their efficacy. Therefore, the drug sustainability and pharmacodynamic properties of...

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Main Authors: Sung-Wook Yoon, Myong-Ji Kim, Kyeong-Won Paeng, Kyeong Ae Yu, Chong-Kil Lee, Young Woo Song, Jae-Kook Cha, Ui-Won Jung
Format: Artigo
Jezik:Inglês
Izdano: MDPI AG 2020-10-01
Serija:Pharmaceutics
Teme:
chitosan-alginate microspheres
drug sustainability
locally applied antibiotics
peri-implantitis
pharmacodynamic
Online dostop:https://www.mdpi.com/1999-4923/12/11/1016
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