Trichostatin A, a Histone Deacetylase Inhibitor, Alleviates Eosinophilic Meningitis Induced by Angiostrongylus cantonensis Infection in Mice

Histone deacetylase inhibitor (HDACi) has been used in the treatment of neurodegenerative or autoimmune diseases. Angiostrongyliasis cantonensis caused by Angiostrongylus cantonensis infection is an emerging zoonosis of human eosinophilic meningitis or meningoencephalitis. Progressive neuronal apopt...

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Detalhes bibliográficos
Main Authors: Yanhua Zhang, Hui Xie, Wenyan Tang, Xingda Zeng, Yu Lin, Lian Xu, Lihua Xiao, Jun Xu, Zhongdao Wu, Dongjuan Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-10-01
Colecção:Frontiers in Microbiology
Assuntos:
trichostatin A
Angiostrongylus cantonensis
eosinophilic meningitis
inflammation
cognitive impairments
HDAC
Acesso em linha:https://www.frontiersin.org/article/10.3389/fmicb.2019.02280/full
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