G-231A and G+70C polymorphisms of endothelin receptor type-A gene could affect the psoriasis area and severity index score and endothelin 1 levels

Background: The etiopathogenesis of psoriasis has not been clearly elucidated although the role of chronic inflammation, imbalance between pro- and anti-inflammatory cytokines, and many immunological events have been established. Endothelin 1 (EDN1) and endothelin receptor type-A (EDNRA) are implica...

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Detalhes bibliográficos
Main Authors: Gökhan Okan, Zeynep Yildiz, Gonca Gökdemir, Eda Yorulmaz, Pervin Vural, Semra Dogru-Abbasoglu, Müjdat Uysal
Formato: Artigo
Idioma:Inglês
Publicado em: Wolters Kluwer Medknow Publications 2015-01-01
Colecção:Indian Journal of Dermatology
Assuntos:
Autoimmune
endothelin family
inflammation
polymorphism
psoriasis
Acesso em linha:http://www.e-ijd.org/article.asp?issn=0019-5154;year=2015;volume=60;issue=2;spage=211;epage=211;aulast=Okan
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