Isorhynchophylline, a Potent Plant Alkaloid, Induces Apoptotic and Anti-Metastatic Effects in Human Hepatocellular Carcinoma Cells through the Modulation of Diverse Cell Signaling Cascades

Isorhynchophylline (Rhy) is an active pharmacological component of Uncaria rhynchophylla that has been reported previously to exert significant antihypertensive and neuroprotective effects. However, very little is known about its potential anti-cancer activities. This study was carried out to evalua...

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Main Authors: Hanwool Lee, Seung Ho Baek, Jong Hyun Lee, Chulwon Kim, Jeong-Hyeon Ko, Seok-Geun Lee, Arunachalam Chinnathambi, Sulaiman Ali Alharbi, Woong Mo Yang, Jae-Young Um, Gautam Sethi, Kwang Seok Ahn
Formáid: Artigo
Teanga:Inglês
Foilsithe: MDPI AG 2017-05-01
Sraith:International Journal of Molecular Sciences
Ábhair:
isorhynchophylline
apoptosis
invasion
migration
cell signaling
Rochtain Ar Líne:http://www.mdpi.com/1422-0067/18/5/1095
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