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COPS2 Antagonizes OCT4 to Accelerate the G2/M Transition of Mouse Embryonic Stem Cells

Summary: Proper regulation of the cell cycle is essential to safeguard the genomic integrity of embryonic stem cells (ESCs) while maintaining the fast proliferation rate. The pluripotency factor OCT4 has been shown to inhibit CDK1 activation, thus preventing mitotic entry and facilitating the mainte...

詳細記述

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書誌詳細
主要な著者: Peng Li, Nan Ding, Weiyu Zhang, Lingyi Chen
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2018-08-01
シリーズ:Stem Cell Reports
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2213671118302765
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