The Cancer Aneuploidy Paradox: In the Light of Evolution

Aneuploidy should compromise cellular proliferation but paradoxically favours tumour progression and poor prognosis. Here, we consider this paradox in terms of our most recent observations of chemo/radio-resistant cells undergoing reversible polyploidy. The latter perform the segregation of two pare...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Kristine Salmina, Anda Huna, Martins Kalejs, Dace Pjanova, Harry Scherthan, Mark S. Cragg, Jekaterina Erenpreisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2019-01-01
Reeks:Genes
Onderwerpen:
cancer
aneuploidy
meio-mitosis
disabled spindle
autokaryogamy
somatic pairing
recombination on kinetochores
reduction
chromothripsis
cleavage embryo
Online toegang:https://www.mdpi.com/2073-4425/10/2/83
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items