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NAD+-Glycohydrolase Promotes Intracellular Survival of Group A Streptococcus.

A global increase in invasive infections due to group A Streptococcus (S. pyogenes or GAS) has been observed since the 1980s, associated with emergence of a clonal group of strains of the M1T1 serotype. Among other virulence attributes, the M1T1 clone secretes NAD+-glycohydrolase (NADase). When GAS...

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Bibliographische Detailangaben
Hauptverfasser: Onkar Sharma, Maghnus O'Seaghdha, Jorge J Velarde, Michael R Wessels
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2016-03-01
Schriftenreihe:PLoS Pathogens
Online Zugang:http://europepmc.org/articles/PMC4777570?pdf=render
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