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Motion as a phenotype: the use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics

<p>Abstract</p> <p>Background</p> <p>Gene transcriptional activity is well correlated with intra-nuclear position, especially relative to the nuclear periphery, which is a region classically associated with gene silencing. Recently however, actively transcribed genes ha...

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Main Authors: Silver Pamela A, Garakani Arman M, Drubin David A
Formáid: Artigo
Teanga:Inglês
Foilsithe: BMC 2006-04-01
Sraith:BMC Cell Biology
Rochtain Ar Líne:http://www.biomedcentral.com/1471-2121/7/19
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