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HIGD1A Regulates Oxygen Consumption, ROS Production, and AMPK Activity during Glucose Deprivation to Modulate Cell Survival and Tumor Growth
Hypoxia-inducible gene domain family member 1A (HIGD1A) is a survival factor induced by hypoxia-inducible factor 1 (HIF-1). HIF-1 regulates many responses to oxygen deprivation, but viable cells within hypoxic perinecrotic solid tumor regions frequently lack HIF-1α. HIGD1A is induced in these HIF-de...
Wedi'i Gadw mewn:
Prif Awduron: | , , , , , , , , , , , , , , , |
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Fformat: | Artigo |
Iaith: | Inglês |
Cyhoeddwyd: |
Elsevier
2015-02-01
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Cyfres: | Cell Reports |
Mynediad Ar-lein: | http://www.sciencedirect.com/science/article/pii/S2211124715000339 |
Tagiau: |
Ychwanegu Tag
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