Combination of Fetal Fraction Estimators Based on Fragment Lengths and Fragment Counts in Non-Invasive Prenatal Testing

The reliability of non-invasive prenatal testing is highly dependent on accurate estimation of fetal fraction. Several methods have been proposed up to date, utilizing different attributes of analyzed genomic material, for example length and genomic location of sequenced DNA fragments. These two sou...

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Main Authors: Juraj Gazdarica, Rastislav Hekel, Jaroslav Budis, Marcel Kucharik, Frantisek Duris, Jan Radvanszky, Jan Turna, Tomas Szemes
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2019-08-01
Serier:International Journal of Molecular Sciences
Fag:
NIPT
fetal fraction
statistical methods
DNA
maternal serum screening
fetal cells
Online adgang:https://www.mdpi.com/1422-0067/20/16/3959
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