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Natural Killer (NK)- and T-Cell Engaging Antibody-Derived Therapeutics

Unmodified antibodies (abs) have been successful in the treatment of hematologic malignancies, but less so for the treatment of solid tumors. They trigger anti-tumor effects through their Fc-domains, and one way to improve their efficacy is to optimize their interaction with the effectors through Fc...

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Detalhes bibliográficos
Main Authors: Christoph Stein, Ingo Schubert, Georg H. Fey
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2012-06-01
Colecção:Antibodies
Assuntos:
Acesso em linha:http://www.mdpi.com/2073-4468/1/1/88
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