Knockdown of XBP1 by RNAi in Mouse Granulosa Cells Promotes Apoptosis, Inhibits Cell Cycle, and Decreases Estradiol Synthesis

Granulosa cells are crucial for follicular growth, development, and follicular atresia. X-box binding protein 1 (XBP1), a basic region-leucine zipper protein, is widely involved in cell differentiation, proliferation, apoptosis, cellular stress response, and other signaling pathways. In this study,...

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Библиографические подробности
Главные авторы: Nan Wang, Fan Zhao, Pengfei Lin, Guangle Zhang, Keqiong Tang, Aihua Wang, Yaping Jin
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI AG 2017-05-01
Серии:International Journal of Molecular Sciences
Предметы:
XBP1
granulosa cells
RNA interference
steroidogenesis
apoptosis
cell cycle
Online-ссылка:http://www.mdpi.com/1422-0067/18/6/1152
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