Knockdown of XBP1 by RNAi in Mouse Granulosa Cells Promotes Apoptosis, Inhibits Cell Cycle, and Decreases Estradiol Synthesis

Granulosa cells are crucial for follicular growth, development, and follicular atresia. X-box binding protein 1 (XBP1), a basic region-leucine zipper protein, is widely involved in cell differentiation, proliferation, apoptosis, cellular stress response, and other signaling pathways. In this study,...

Full description

Saved in:
Bibliographic Details
Main Authors: Nan Wang, Fan Zhao, Pengfei Lin, Guangle Zhang, Keqiong Tang, Aihua Wang, Yaping Jin
Format: Artigo
Language:Inglês
Published: MDPI AG 2017-05-01
Series:International Journal of Molecular Sciences
Subjects:
XBP1
granulosa cells
RNA interference
steroidogenesis
apoptosis
cell cycle
Online Access:http://www.mdpi.com/1422-0067/18/6/1152
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items