Solid-Phase Synthesis of Head to Side-Chain Tyr-Cyclodepsipeptides Through a Cyclative Cleavage From Fmoc-MeDbz/MeNbz-resins

Cyclic depsipeptides constitute a fascinating class of natural products. Most of them are characterized by an ester formed between the β-hydroxy function of Ser/Thr -and related amino acids- and the carboxylic group of the C-terminal amino acid. Less frequent are those where the thiol of Cys is invo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gerardo A. Acosta, Laura Murray, Miriam Royo, Beatriz G. de la Torre, Fernando Albericio
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020-04-01
Cyfres:Frontiers in Chemistry
Pynciau:
cyclothiodepsipeptides
heterodetic cyclic peptides
homodetic cyclic peptides
native chemical ligation
solid-phase peptide synthesis
Mynediad Ar-lein:https://www.frontiersin.org/article/10.3389/fchem.2020.00298/full
Tagiau: Ychwanegu Tag
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