Solid-Phase Synthesis of Head to Side-Chain Tyr-Cyclodepsipeptides Through a Cyclative Cleavage From Fmoc-MeDbz/MeNbz-resins

Cyclic depsipeptides constitute a fascinating class of natural products. Most of them are characterized by an ester formed between the β-hydroxy function of Ser/Thr -and related amino acids- and the carboxylic group of the C-terminal amino acid. Less frequent are those where the thiol of Cys is invo...

Full description

Saved in:
Bibliographic Details
Main Authors: Gerardo A. Acosta, Laura Murray, Miriam Royo, Beatriz G. de la Torre, Fernando Albericio
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Chemistry
Subjects:
cyclothiodepsipeptides
heterodetic cyclic peptides
homodetic cyclic peptides
native chemical ligation
solid-phase peptide synthesis
Online Access:https://www.frontiersin.org/article/10.3389/fchem.2020.00298/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items