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α-Synuclein in the Synaptic Vesicle Liquid Phase: Active Player or Passive Bystander?

The protein α-synuclein, which is well-known for its links to Parkinson’s Disease, is associated with synaptic vesicles (SVs) in nerve terminals. Despite intensive studies, its precise physiological function remains elusive. Accumulating evidence indicates that liquid-liquid phase separation takes p...

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Bibliographic Details
Main Authors: Lennart Brodin, Dragomir Milovanovic, Silvio O. Rizzoli, Oleg Shupliakov
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Molecular Biosciences
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Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.891508/full
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