Comprehensive Profile of Acute Mitochondrial Dysfunction in a Preclinical Model of Severe Penetrating TBI

Mitochondria constitute a central role in brain energy metabolism, and play a pivotal role in the development of secondary pathophysiology and subsequent neuronal cell death following traumatic brain injury (TBI). Under normal circumstances, the brain consumes glucose as the preferred energy source...

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Detalhes bibliográficos
Principais autores: Jignesh D. Pandya, Lai Yee Leung, Xiaofang Yang, William J. Flerlage, Janice S. Gilsdorf, Ying Deng-Bryant, Deborah A. Shear
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019-06-01
coleção:Frontiers in Neurology
Assuntos:
traumatic brain injury (TBI)
penetrating ballistic-like brain injury (PBBI)
alternative biofuels
brain energy metabolism
energy crisis
mitochondria preferred substrates
Acesso em linha:https://www.frontiersin.org/article/10.3389/fneur.2019.00605/full
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