Aberrant crypt foci and colon cancer: comparison between a short- and medium-term bioassay for colon carcinogenesis using dimethylhydrazine in Wistar rats

Aberrant crypt foci (ACF) in the colon of carcinogen-treated rodents are considered to be the earliest hallmark of colon carcinogenesis. In the present study the relationship between a short-term (4 weeks) and medium-term (30 weeks) assay was assessed in a model of colon carcinogenesis induced by di...

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Main Authors: Rodrigues M.A.M., Silva L.A.G., Salvadori D.M.F., de Camargo J.L.V., Montenegro M.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Associação Brasileira de Divulgação Científica 2002-01-01
Colecção:Brazilian Journal of Medical and Biological Research
Assuntos:
Aberrant crypt foci
Preneoplastic lesion
Colon carcinogenesis
Acesso em linha:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2002000300010
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