Senescence in Monocytes Facilitates Dengue Virus Infection by Increasing Infectivity

Aging and chronic condition increase the incidence of dengue virus (DENV) infection, generally through a mechanism involving immunosenescence; however, the alternative effects of cellular senescence, which alters cell susceptibility to viral infection, remain unknown. Human monocytic THP-1 cells (AT...

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Detalhes bibliográficos
Main Authors: Tzu-Han Hsieh, Tsung-Ting Tsai, Chia-Ling Chen, Ting-Jing Shen, Ming-Kai Jhan, Po-Chun Tseng, Chiou-Feng Lin
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020-07-01
Colecção:Frontiers in Cellular and Infection Microbiology
Assuntos:
dengue virus
senescence
IL-10
DC-SIGN
monocytes
Acesso em linha:https://www.frontiersin.org/article/10.3389/fcimb.2020.00375/full
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