DNA Methylation in Noncancerous Liver Tissues as Biomarker for Multicentric Occurrence of Hepatitis C Virus–Related Hepatocellular Carcinoma

Background and Aims: Hepatitis C virus (HCV)-related hepatocellular carcinoma (HCC) progresses with a highly multicentric occurrence (MO) even after radical hepatectomy. Despite several efforts to clarify the pathogenesis of MO, the underlying molecular mechanism remains elusive. The aim of this stu...

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Hauptverfasser: Hiroyuki Suzuki, Hideki Iwamoto, Ken Yamamoto, Mai Tsukaguchi, Toru Nakamura, Atsutaka Masuda, Takahiko Sakaue, Toshimitsu Tanaka, Takashi Niizeki, Shusuke Okamura, Shigeo Shimose, Tomotake Shirono, Yu Noda, Naoki Kamachi, Ryoko Kuromatsu, Toru Hisaka, Hirohisa Yano, Hironori Koga, Takuji Torimura
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2022-01-01
Schriftenreihe:Gastro Hep Advances
Schlagworte:
Hepatocellular Carcinoma
DNA Methylation
Hepatitis C Virus
Multicentric Occurrence
Online Zugang:http://www.sciencedirect.com/science/article/pii/S2772572322000346
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