EIF4A3-induced circTOLLIP promotes the progression of hepatocellular carcinoma via the miR-516a-5p/PBX3/EMT pathway

Abstract Background Circular RNAs (circRNAs) function as crucial regulators in multiple cancers, including hepatocellular carcinoma (HCC). However, the roles of circRNAs in HCC remains largely unknown. Methods circTOLLIP was identified in HCC by screening of two public circRNA microarray datasets an...

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Main Authors: Yachong Liu, Jia Song, Hongwei Zhang, Zhibin Liao, Furong Liu, Chen Su, Weijian Wang, Mengzhen Han, Lu Zhang, He Zhu, Zhanguo Zhang, Huifang Liang, Lei Zhang, Bixiang Zhang, Xiaoping Chen
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-05-01
Serier:Journal of Experimental & Clinical Cancer Research
Fag:
circTOLLIP
HCC
PBX3
EMT
Online adgang:https://doi.org/10.1186/s13046-022-02378-2
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