Progressive retinal degeneration and glial activation in the CLN6 (nclf) mouse model of neuronal ceroid lipofuscinosis: a beneficial effect of DHA and curcumin supplementation.

Neuronal ceroid lipofuscinosis (NCL) is a group of neurodegenerative lysosomal storage disorders characterized by vision loss, mental and motor deficits, and spontaneous seizures. Neuropathological analyses of autopsy material from NCL patients and animal models revealed brain atrophy closely associ...

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Huvudupphovsmän: Myriam Mirza, Cornelia Volz, Marcus Karlstetter, Monica Langiu, Aleksandra Somogyi, Mika O Ruonala, Ernst R Tamm, Herbert Jägle, Thomas Langmann
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science (PLoS) 2013-01-01
Serie:PLoS ONE
Länkar:http://europepmc.org/articles/PMC3790850?pdf=render
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